ISARIIN, A NEW DEPSIPEPTIDE FROM ISARIA CRETACEA
نویسندگان
چکیده
منابع مشابه
A new depsipeptide antibiotic, citropeptin.
An actinomycete identified as Streptomyces flavidovirens was found to produce a new cyclic hexadepsipeptide antibiotic, designated citropeptin. Citropeptin showed antitumor activity against P388 murine leukemia.
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A culture similar to Streptomyces variabilis was found to produce a novel cyclic hexadepsipeptide antibiotic named variapeptin. Variapeptin is structurally related to azinothricin, A83586C, and citropeptin. The antibiotic was active against Gram-positive bacteria and showed cytotoxic activity against mammalian cells.
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A new depsipeptide antibiotic, vinylamycin, was isolated from the culture broth of an actinomycete strain. The producing organism, designated MI982-63F1, was identified as a member of Streptomyces. Vinylamycin was isolated from the culture broth by extraction with EtOAc and purified by crystallization from EtOAc. The structure of vinylamycin was determined by spectroscopic analysis and degradat...
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Arthogalin is a neutral compound of the m.p. 285-286 °C and gives no reaction with KOH, NaOCl, KOH + NaOCl, FeCl3 or /?-phenylenediamine. The high resolution MS yielded the for mula C24H 34N20 6 (found 446.225, ealed 446.242) and the NMR spectrum showed that arthogalin is a cyclic depsipeptide composed of one molecule of phenylalanine, one molecule of valine and two molecules of a-hydroxyisova...
متن کاملStructural studies on new depsipeptide antibiotics, variapeptin and citropeptin.
Variapeptin and citropeptin were found as novel hexadepsipeptide antibiotics produced by Streptomyces variabilis and Streptomyces flavidovirens, respectively. Their structures were elucidated by NMR spectral analysis including a variety of 2D techniques. Variapeptin and citropeptin are structurally realted to azinothricin and A83586C, respectively.
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ژورنال
عنوان ژورنال: Canadian Journal of Chemistry
سال: 1962
ISSN: 0008-4042,1480-3291
DOI: 10.1139/v62-239